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31 October 2025 : Clinical Research  

Comparative Oncologic Outcomes in High-Risk Human Papillomavirus-Positive and -Negative Cervical Intraepithelial Neoplasia

Saliha Sağnıç ORCID logo ABCDEF 1*, Serap Fırtına Tuncer ORCID logo ABCF 2, Hasan Aykut Tuncer ORCID logo CDF 1, Selen Doğan ORCID logo ADF 1, Tayup Şimşek ORCID logo ADF 1

DOI: 10.12659/MSM.950452

Med Sci Monit 2025; 31:e950452

Table 3 Comparison of baseline characteristics of patients who did and did not undergo hysterectomy.

CharacteristicsNo hysterectomy (n=497)Hysterectomy (n=64)P value
38.0 [11.0]44.5 [8.0]
24.1 [5.6]26.1 [7.4]
2.0 [2.0]3.0 [2.0]
2.0 [1.0]1.0 [0.0]
 NVD255 (51.3)49 (76.6)
 CS96 (19.3)6 (9.4)
 NVD+CS44 (8.9)8 (12.4)
 None102 (20.5)1 (1.6)
 No430 (86.5)48 (75)
 Yes67 (13.5)16 (25)
p=0.781
 No453 (91.1)59 (92.2)
 Yes44 (8.9)5 (7.8)
 Ever smoked288 (57.9)26 (40.6)
 Never smoked209 (42.1)38 (59.4)
 None229 (46.1)39 (60.9)
 Using268 (53.9)25 (39.1)
p=0.509
 Positive445 (89.5)59 (92,2)
 Negative52 (10,5)5 (7.8)
p<0.001
 Negative400 (80.5)23 (35.9)
 Positive91 (18.3)41 (64.1)
 Unassessable6 (1.2)
IQR – interquartile range; BMI – body mass index; NVD – normal vaginal delivery; CS – cesarean section.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750