06 January 2026 : Review article
ECMO-Assisted In-Situ Normothermic Perfusion for Donation After Circulatory Determination of Death Kidney Transplantation: A Narrative Review
Jan Roman
ABDEF 1,2, Franišek Jalůvka BEF 1,2*, Filip Burša DEF 2,3, Petr Jelínek ABF 1,2, Petr Ostruszka DEF 1, Pavel Havránek ADE 4, Jan Mandrla EF 1, Vaclav Prochazka DE 2,5
DOI: 10.12659/MSM.950817
Med Sci Monit 2026; 32:e950817
Table 1 Summary of results of normothermic regional perfusion (NRP) in kidney transplantation.
| Study | Scenario | Kidneys transplanted using NRP (n) | DGFn (%) | PNFn (%) | 1-Year graft survival % | 1-Year patient survival % |
|---|---|---|---|---|---|---|
| Valero et al (2000) []14 | uDCDD | 8 | 1 (12.5) | 0 (0.0) | 76.4 | 89.3 |
| Miñambres et al (2017) []20 | cDCDD | 37 | 10 (27.0) | – | 91.8 | – |
| Foss et al (2018) []16 | cDCDD | 8 | 1 (7.1) | – | 93.0 | – |
| Molina et al (2019) []27 | uDCDD | 237 | 174 (73.4) | 16 (6.8) | – | – |
| Antoine et al (2020) []19 | uDCDD | 251 | – | 15 (6.0) | – | – |
| Salguero et al (2024) []17 | cDCDD | 19 | 1 (5.3) | 1 (5.3) | – | – |
| DGF – delayed graft function; PNF – primary non-function; cDCDD – controlled scenario of donors after circulatory determination of death; uDCDD – uncontrolled scenario of donors after circulatory determination of death. | ||||||