18 October 2025 : Clinical Research
Clinical Outcomes and Prognostic Factors in Cerebral Abscess: Hyperglycemia as a Predictor of the Need for Prolonged Antibiotic Therapy
Joon O Park BCDEF 1,2, Seongwoo Lee BCDF 1, Jang Hun Kim ACDE 1, Dong-Hyuk Park BCDE 1, Shin-Hyuk Kang BCDEF 1, Kyung-Jae Park ADEFG 1*DOI: 10.12659/MSM.950987
Med Sci Monit 2025; 31:e950987
Table 1 Baseline demographic and clinical characteristics of the patients (n=112).
| Data | Number of patients (%) |
|---|---|
| Age (median, range) | 54 (11–83) |
| Sex ratio (Male/Female) | 90 (80)/22 (20) |
| Symptoms and signs | |
| Headache | 57 (51) |
| Hemiparesis/hemiplegia | 42 (38) |
| Fever | 21 (19) |
| Dysarthria/aphasia | 17 (15) |
| Confusion | 16 (14) |
| Visual disturbance | 13 (12) |
| Seizure | 10 (9) |
| General weakness/malaise | 9 (4) |
| Sensory abnormality | 8 (4) |
| Cognitive decline | 7 (6) |
| Nausea/vomiting | 5 (4) |
| Voiding disturbance | 4 (2) |
| Symptom duration (median, range) | 7 (0–56) |
| GCS upon admission | |
| ≥13 | 90 (80) |
| <13 | 22 (20) |
| Predisposing source | 52 (46) |
| Pulmonary infection (pneumonia, abscess) | 15 (12) |
| Paranasal infection (sinusitis) | 9 (8) |
| Dental infection | 8 (7) |
| Inner ear infection | 6 (5) |
| Previous trauma or neurosurgery | 6 (5) |
| Endocarditis | 3 (3) |
| Liver abscess | 2 (2) |
| Cutaneous infection | 2 (2) |
| Musculoskeletal infection (psoas abscess) | 1 (1) |
| Known diabetes | 20 (18) |
| Immunocompromised status | 10 (9) |
| Chemotherapy | 5 (4) |
| Chronic renal failure | 3 (3) |
| Addison’s disease | 1 (1) |
| Systemic lupus erythematosus | 1 (1) |
| GCS – Glasgow Coma Scale. | |