14 December 2025 : Clinical Research
The Silent Face of Chronic Hepatitis B: Biopsy-Supported Fibrosis Detection and the Reliability of Non-Invasive Scores (FIB-4, APRI) in Inactive, Gray Zone, and Immune-Tolerant Cases
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DOI: 10.12659/MSM.951084
Med Sci Monit 2025; 31:e951084
Table 4 Pairwise comparison of ROC curves for predicting fibrosis score ≥3 (FIB-4 vs APRI).
| Difference between areas | Difference between areas (95% confidence interval) | P value |
|---|---|---|
| FIB-4-APRI | 0.01 (−0.07 to 0.09) | 0.80 |
| APRI – Aspartate Aminotransferase-to-Platelet Ratio Index; FIB-4 – Fibrosis-4 Index; ROC – receiver operating characteristic. | ||