31 March 2026 : Clinical Research
Development and Validation of a Predictive Model Combining [18F] FDG PET/CT and the Suidan Score for Primary Optimal Cytoreduction in Advanced High-Grade Serous Ovarian Cancer: A Retrospective Cohort Study
Xiaohang Lu ACE 1, Xiaomei Wang CD 2, Shengnan Wang BC 1, Jiazhen Huang DE 1, Wei Wei EF 1, Fuli Kang EF 1, Ning Wang AFG 1*DOI: 10.12659/MSM.951183
Med Sci Monit 2026; 32:e951183
Table 1 Patient and tumor characteristics.
| Characteristics | Total cohort (n=110) | Training cohort (n=70) | Validation cohort (n=40) | P |
|---|---|---|---|---|
| Age (years) | 59 (37, 77) | 58 (37, 77) | 61.5 (43, 75) | 0.083 |
| FIGO stage | ||||
| IIIC | 54 (49.09%) | 37 (52.86%) | 17 (42.5%) | 0.296 |
| IV | 56 (50.91%) | 33 (47.14%) | 23 (57.5%) | |
| CA125 (U/mL) | 650.10 (376.34, 1762.75) | 734.4 (373.74, 1842.41) | 619.65 (377.11, 1306.25) | 0.294 |
| ALB (g/L) | 37.08±5.32 | 36.73±4.86 | 37.70±6.06 | 0.362 |
| BMI (kg/m) | 23.30±3.17 | 22.98±3.20 | 23.85±3.08 | 0.168 |
| Hb (g/L) | 122.82±14.12 | 121.99±13.46 | 124.28±15.29 | 0.416 |
| Surgery time (min) | 376.25±116.88 | 389.49±121.56 | 353.10±105.69 | 0.117 |
| Blood loss (mL) | 400 (200, 1000) | 500 (200, 1220) | 300 (125, 475) | 0.015 |
| Residual | ||||
| R0 | 81 (73.64%) | 51 (72.86%) | 30 (75%) | 0.806 |
| R1 | 29 (26.36%) | 19 (27.14%) | 10 (25%) | |
| * Data are presented as median (interquartile range) for non-normally distributed continuous variables, mean±standard deviation for normally distributed continuous variables, and number (percentage) for categorical variables. Percentages are calculated based on the column totals (denominators: Total=110, Training=70, Validation=40). No data were missing for the presented variables. values compare the training and validation cohorts using the Wilcoxon rank-sum test for non-normally distributed continuous variables, independent test for normally distributed continuous variables, and chi-squared test for categorical variables. R0 resection was defined as no macroscopic residual disease. ALB – albumin; BMI – body mass index; Hb – hemoglobin. | ||||