25 January 2026 : Clinical Research
Comparison of Ciprofol-Nalbuphine and Propofol-Nalbuphine Sedation During Painless Gastrointestinal Endoscopy: A Randomized Controlled Trial
Zhong Zhang BCE 1, Wei Jiang ABF 1, Longjiao Zheng BCF 1, Zhiyang Yu ACDE 1*DOI: 10.12659/MSM.951195
Med Sci Monit 2026; 32:e951195
Table 1 Patient demographics and baseline values.
| Variable | Propofol (n=64) | Ciprofol (n=64) | χ2/t | P |
|---|---|---|---|---|
| Age (years) | 44.9±10.6 | 45.0±10.6 | 0.25 | 0.980 |
| Sex | ||||
| Male | 29 (45.3%) | 33 (50.7%) | 0.479 | 0.500 |
| Female | 35 (54.7%) | 31 (49.3%) | ||
| Height (cm) | 165.0±6.9 | 165.5±7.9 | 0.425 | 0.671 |
| Weight (kg) | 62.9±11.7 | 65.4±11.2 | 1.220 | 0.225 |
| BMI (kg/m) | 23.0±3.1 | 23.8±2.8 | 1.571 | 0.132 |
| ASA physical status | 0.516 | 0.422 | ||
| I grade | 52 | 49 | ||
| II grade | 12 | 15 | ||
| Comorbidities | 0.884 | 0.248 | ||
| HBP history | 7 (10.9%) | 7 (10.9%) | ||
| DM history | 4 (6.3%) | 6 (9.3%) | ||
| Hypothyroidism | 1 (1.6%) | 2 (3.1%) | ||
| Data were presented as mean (SD) or n (%), as appropriate. BMI – body mass index; ASA – American Society of Anesthesiologists; HBP – high blood pressure; DM – diabetes mellitus. | ||||






