25 January 2026 : Clinical Research
Comparison of Ciprofol-Nalbuphine and Propofol-Nalbuphine Sedation During Painless Gastrointestinal Endoscopy: A Randomized Controlled Trial
Zhong Zhang BCE 1, Wei Jiang ABF 1, Longjiao Zheng BCF 1, Zhiyang Yu ACDE 1*DOI: 10.12659/MSM.951195
Med Sci Monit 2026; 32:e951195
Table 5 Satisfaction (visual analog scale, 0–10) and postprocedural assessments.
| Variable | Propofol (n=64) | Ciprofol (n=64) | χ2/t | P |
|---|---|---|---|---|
| Endoscopists | 8.4±1.1 | 9.1±1.0 | 3.686 | <0.001 |
| Anesthesiologist | 7.5±1.3 | 8.7±1.1 | 5.637 | <0.001 |
| Patient cooperation by observer | 8.4±0.5 | 9.3±0.5 | 10.676 | <0.001 |
| Abdominal pain or distention after awakening | 33 (51.6%) | 25 (39.1%) | 2.018 | 0.155 |
| Fatigue after awakening | 23 (35.9%) | 21 (32.8%) | 0.135 | 0.710 |
| Dream | 16 (25%) | 15 (23.4%) | 0.043 | 0.837 |
| Nausea and vomiting | 6 (9.4%) | 2 (3.1%) | 1.200 | 0.273 |