13 April 2026 : Clinical Research
Diagnostic Value of End-Tidal Carbon Dioxide Combined With Lactate for Early Detection of Sepsis in Prehospital Patients: A Prospective Cohort Study
Hui Jiang ABCDEF 1,2, Zhihui Xie ADEF 1, Jie Xiang ABE 1, Huiting Wang ACDF 3*, Liu Yang ABEF 1DOI: 10.12659/MSM.951586
Med Sci Monit 2026; 32:e951586
Table 3 Sensitivities and specificities with 95% confidence intervals for different ETCO2 and hyperlactatemia combinations in diagnosing prehospital sepsis.
| 95% CI | ||
|---|---|---|
| Sensitivity | Specificity | |
| ETCO ≤25 mmHg | 82.9 (76.3–88.2) | 81.7 (77.5–85.4) |
| ETCO ≤30 mmHg | 77.3 (70.5–83.2) | 75.1 (70.8–79.0) |
| ETCO ≤25 mmHg+hyperlactatemia | 89.9 (84.8–93.7) | 91.7 (88.2–94.4) |
| ETCO ≤30 mmHg+hyperlactatemia | 80.1 (73.6–85.5) | 79.1 (75.0–82.8) |