29 December 2025 : Clinical Research
Predictive Value of Preoperative Neutrophil-to-Lymphocyte Ratio (NLR) and Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) for Biochemical Recurrence After Radical Prostatectomy
Hui Wang ABCDEFG 1*, Chenxi Huang BDE 2DOI: 10.12659/MSM.951769
Med Sci Monit 2025; 31:e951769
Table 1 Clinical baseline characteristics of the study population.
| Variable | Non-BCR (n=183) | BCR (n=62) | t/χ2 | P |
|---|---|---|---|---|
| Age (years) | 62.17±5.20 | 63.03±5.48 | 1.106 | 0.270 |
| BMI (kg/m) | 23.56±1.41 | 23.73±1.53 | 0.817 | 0.415 |
| Preoperative PSA (ng/mL) | ||||
| <20 | 88 (48.09%) | 18 (29.03%) | 6.850 | 0.009 |
| ≥20 | 95 (51.91%) | 44 (70.97%) | ||
| Gleason Score | ||||
| <8 | 110 (60.11%) | 25 (40.32%) | 7.329 | 0.007 |
| ≥8 | 73 (39.89%) | 37 (59.68%) | ||
| Total prostate volume (mL) | 34.68±4.45 | 35.58±4.68 | 1.363 | 0.174 |
| Pathologic T stage (n, %) | ||||
| T2 | 116 (63.39%) | 27 (43.55%) | 7.501 | 0.006 |
| T3–T4 | 67 (36.61%) | 35 (56.45%) | ||
| Seminal vesicle invasion (n, %) | 47 (25.68%) | 27 (43.55%) | 7.011 | 0.008 |
| Positive surgical margins (n, %) | 19 (10.38%) | 17 (27.42%) | 10.721 | 0.001 |
| Categorical data were presented as number (percentage), and analyzed using the Chi-square test. Normally distributed continuous data were expressed as mean±standard deviation, and comparisons between the two groups were performed using the t-test. A -value | ||||