Core-Out Fistulectomy Combined With Laser Ablation of the Trans-Sphincteric Fistula Tract: A Pilot Study of Efficacy and Safety

Emre Özoran; Sündüs Zeynep Küçüksümer Ertek; Mert Mahsuni Sevinç

doi:10.12659/MSM.951819

03 March 2026 : Clinical Research

Core-Out Fistulectomy Combined With Laser Ablation of the Trans-Sphincteric Fistula Tract: A Pilot Study of Efficacy and Safety

Emre Özoran

^{ABCDEF 1*}, Sündüs Zeynep Küçüksümer Ertek

^{BCDEF 2}, Mert Mahsuni Sevinç

^{AEF 3}

DOI: 10.12659/MSM.951819

Med Sci Monit 2026; 32:e951819

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Table 2 Studies on LAFT.

	Number of [atients	Primary healing rate (percent)	Follow-up time (months)	Preoperative imaging	Use of bridging seton	Modality for internal orifice
Ozturk et al []¹⁰	50	82	12	MRI	Yes	No closure
Wilhelm et al []¹⁸	117	64.1	25.4	Proctosigmoidoscopy & endoanal ultrasonography	Yes	Flap closure
Dönmez et al []²²	27	89	22	Proctosigmoidoscopy & MRI	None	No closure
Terzi et al []²³	103	28	40	Proctosigmoidoscopy & MRI	None	No closure
Lauretta et al []¹⁹	30	33.3	11.3	Endoanal ultrasonography	Yes	No closure
Lauretta et al []¹⁹	30	33.3	11.3	Endoanal ultrasonography	(in 26 patients)	No closure
Marref et al []²⁴	69	45.6	6.3	Not routinely used	Yes	No closure
Stijns et al []²⁵	20	20	10	MRI	Yes	No closure
Stijns et al []²⁵	20	20	10	MRI	(In 15 patients)	No closure
Alam et al []²¹	20	55	7.1	Not specified		No closure
de Bonnechose et al []²⁶	100	44.6	13.6	Not routinely used	Yes	No closure
Brabender et al []¹³	18	22	29	Not routinely used	None	Sutured
Isık et al []²⁰	100	62	48	MRI	Yes	No closure
Serin et al []¹⁴	35	42.9	11	Proctosigmoidoscopy & MRI	None	Suture closure
Wolicki et al []¹⁵	83	74.7	42	Endoanal ultrasonography & MRI (If necessary)	Yes	Suture closure
Wolicki et al []¹⁵	83	74.7	42	Endoanal ultrasonography & MRI (If necessary)	(In 65 patients)	Suture closure
Nordholm-Carstensen et al []¹⁶	66	44.1	19	Endoanal ultrasonography	None	Suture closure
Giamundo et al []¹⁷	175	66.8	60	Proctosigmoidoscopy & endoanal ultrasonography & MRI (if needed)	Yes (In 16 patients)	Suture closure in 27 patients, no closure in 148 patients
Present study	20	90	9.9	MRI	4 patients had setons	Suture closure


Ozturk et al []¹⁰	No excision	0	50	10	0	40	18.0
Wilhelm et al []¹⁸	Excised	13	104	8	6	103	12.0
Dönmez et al []²²	No excision	Not specified	27	14	5	7	11.11
Terzi et al []²³	No excision	0	103	56	11	29	60.0
Lauretta et al []¹⁹	No excision	0	30	0	0	30	66.7
Marref et al []²⁴	No excision	6	63	2	11	56	54.4
Stijns et al []²⁵	No excision	0	20	6	0	14	80.00
Alam et al []²¹	No excision	20	0	1	1	18	45.0
de Bonnechose et al []²⁶	No excision	10	90	0	13	87	55.4
Brabender et al []¹³	No excision	4	14	5	14	1	78.0
Isık et al []²⁰	No excision	0	100	10	8	80	38.0
Serin et al []¹⁴	No excision	0	35	21	2	12	57.1
Wolicki et al []¹⁵	Excised	2	81	Not specified	Not specified	Not specified	21.7
Nordholm-Carstensen et al []¹⁶	Excised	11	55	2	59	5	55.9
Giamundo et al []¹⁷	No excision	0	174	18	5	152	21.7
Present study	Core-out excision of the fistula tract	0	20	0	0	20	10.00
The studies were placed in the table according to publication date. MRI – magnetic resonance imaging of the perianal region; BMI – body mass index.

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Core-Out Fistulectomy Combined With Laser Ablation of the Trans-Sphincteric Fistula Tract: A Pilot Study of Efficacy and Safety

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