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26 April 2026 : Meta-Analysis  

Influence of Operative Techniques on Clinical and Laboratory Outcomes in Class II Resin-Based Composite Restorations: A Systematic Review

Bassam Zidane ORCID logo ABCDEF 1*

DOI: 10.12659/MSM.951980

Med Sci Monit 2026; 32:e951980

Table 7 Evidence mapping matrix: operative techniques vs clinical outcomes.

Operative techniqueLongevityMarginal adaptationPostop sensitivitySecondary caries
Multi-step adhesive protocol Strong Strong Moderate Moderate
Self-etch adhesive (deep boxes) Moderate Moderate Strong ↔ Limited
Incremental layering Strong Moderate Strong Weak
Bulk-fill (unsupported)↓ Weak↓ Moderate↓ Weak↓ Weak
Bulk-fill (with control)↔ Mixed↔ Mixed↔ Mixed↓ Weak
Sectional matrix Moderate Strong Moderate Weak
Circumferential matrix↓ Weak↓ Moderate↔ Neutral↓ Weak
Soft-start curing Moderate Strong Moderate ↔ Limited
Aggressive curing↓ Moderate↓ Moderate↓ Weak↓ Weak
↑ – positive association; ↑↑ – strong association; ↓ – negative association; ↔ – mixed/neutral evidence.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750