08 June 2026 : Clinical Research
Cesarean Scar Pregnancy and Subsequent Obstetric Outcomes: Focus on Postpartum Hemorrhage and Predictive Factors
Xuemin Wei BCDEF 1, Zhida Qian ADEG 1*DOI: 10.12659/MSM.951981
Med Sci Monit 2026; 32:e951981
Table 2 Pregnancy outcomes of patients with and without prior cesarean scar pregnancy.
| Pregnancy outcomes | Prior CSP (n=83) | No-CSP (n=15356) | P |
|---|---|---|---|
| Gestational age (weeks) | 37.08±2.21 | 38.21±1.08 | <0.001 |
| Placenta previa | 23 (27.71%) | 670 (4.36%) | <0.001 |
| PAS | 26 (31.33%) | 566 (3.69%) | <0.001 |
| Prenatal hemorrhage | 8 (9.64%) | 43 (0.26%) | <0.001 |
| Postpartum hemorrhage (≥1000 mL) | 20 (24.09%) | 267 (1.74%) | <0.001 |
| Severe postpartum hemorrhage (≥2000 mL) | 4 (4.82%) | 19 (0.12%) | <0.001 |
| Emergency cesarean section | 12 (14.46%) | 1003 (6.53%) | 0.004 |
| Uterine rupture or threatened uterine rupture | 3 (3.61%) | 29 (0.19%) | <0.001 |
| Hysterectomy | 2 (2.41%) | 3 (0.02%) | <0.001 |
| Preterm delivery (<37 weeks) | 23 (27.71%) | 968 (6.30%) | <0.001 |
| Preterm delivery (<33 weeks) | 7 (8.43%) | 101 (0.66%) | <0.001 |
| Birth weight (g) | 3061.87±643.165 | 3334.56±432.235 | <0.001 |
| Low birth weight | 13 (15.66%) | 451 (2.94%) | <0.001 |
| SGA | 3 (3.61%) | 93 (0.61%) | 0.005 |
| LGA | 2 (2.41%) | 759 (4.94%) | 0.419 |
| Apgar score (<4 at 1 minute) | 1 (1.20%) | 21 (0.14%) | 0.265 |
| Apgar score (<7 at 5 minutes) | 1 (1.20%) | 10 (0.07%) | 0.069 |
| NICU admission | 10 (12.05%) | 482 (3.14%) | <0.001 |
| Data are presented as mean±standard deviation, median (interquartile range), or n (%). CSP – cesarean scar pregnancy; LGA – large for gestational age; NICU – neonatal intensive care unit; PAS – placenta accreta spectrum; SGA – small for gestational age. | |||