25 April 2026 : Clinical Research
Long-Term Endothelial Outcomes and Dislocation Risks in Small Versus Large Grafts for Descemet’s Stripping Endothelial Keratoplasty
Yingxin Chen ABEG 1*, Jiaxin Xiao ABCDEF 1, Ruiyao Gao BCD 1, Zhida You BCD 1, Yanhong Ba B 1DOI: 10.12659/MSM.952103
Med Sci Monit 2026; 32:e952103
Table 1 Baseline characteristics and surgical procedures in the small-graft and large-graft groups of patients.
| Small-graft group (n=28) | Large-graft group (n=34) | P-value | |
|---|---|---|---|
| Age (years, mean±SD) | 67.14±8.52 | 65.59±11.73 | 0.560 |
| Gender (n,%) | 0.818 | ||
| Female | 14 (50.00%) | 18 (52.94%) | |
| Male | 14 (50.00%) | 16 (47.06%) | |
| Preoperative BCVA (logMAR, mean±SD) | 1.93±0.88 | 1.75±0.87 | 0.414 |
| History of glaucoma (n,%) | 6 (21.43%) | 10 (29.41%) | 0.475 |
| Graft thickness (μm, mean±SD) | 101.70±3.44 | 101.06±4.84 | 0.507 |
| Status of the crystalline lens (n,%) | 0.276 | ||
| Phakic | 16 (57.14%) | 22 (64.71%) | |
| Pseudophakic | 10 (35.72%) | 12 (35.29%) | |
| Aphakic | 2 (7.14%) | 0 | |
| Surgical procedures (n,%) | 0.923 | ||
| DSEK | 19 (67.86%) | 25 (73.53%) | |
| DSEK + phacoemulsification + IOL implantation | 5 (17.86%) | 5 (14.71%) | |
| DSEK + pupilloplasty | 1 (3.57%) | 2 (5.88%) | |
| DSEK + IOL implantation/respositioning + GSL + pupilloplasty | 1 (3.57%) | 1 (2.94%) | |
| DSEK + phacoemulsification + IOL implantation + iridodialysis repair | 2 (7.14%) | 1 (2.94%) | |
| SD – standard deviation; BCVA – best-corrected visual acuity; DSEK – Descemet’s stripping endothelial keratoplasty; IOL – intraocular lens; GSL – goniosynochiolysis. | |||