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25 May 2026 : Clinical Research  

Perioperative Glycemic Control and Outcomes in Cardiac Surgery: A Retrospective Cohort Study

Ana Luiza Antony Gomes de Matos da Costa e Silva ORCID logo ABCDEF 1*, Letícia Maia Zica ORCID logo ABCDEFG 2, Dilson Palhares Ferreira ORCID logo CDEF 1,3, Adda Cecília Batista de Carvalho Vieira ORCID logo CDEF 1, Mauro de Deus Passos ORCID logo CDEF 1, Adegil Henrique Miguel de Melo Silva ORCID logo ABEF 4, Leila Bernarda Donato Gottems ORCID logo DEF 5, Marcio Garrison Dytz ORCID logo ABDF 6, Fábio Ferreira Amorim ORCID logo BCDEF 7

DOI: 10.12659/MSM.952210

Med Sci Monit 2026; 32:e952210

Table 2 Univariate analysis of factors associated with in-hospital mortality.

VariableSurvivor (n=143)Non-survivor (n=14)P value
Age, years, mean (SD)59.3 (13.2)64.1 (11.0)0.184
Female, n (%)53 (37.1)8 (57.1)0.141
Corticosteroid use, n (%)45 (31.5)11 (78.6)< 0.001
DM, n (%)61 (42.7)4 (28.6)0.307
SAH, n (%)92 (64.3)5 (35.7)0.035
Dyslipidemia, n (%)77 (53.8)7 (50.0)0.783
BMI, mean (SD)# 26.9 (5.0)25.3 (4.4)0.120
Surgery type, n (%)0.008
 MR75 (52.4)4 (28.6)
 Heart valve36 (25.2)9 (64.3)
 HTx28 (19.6)0 (0.0)
 Other4 (2.8)1 (7.1)
Underweight, n (%)5 (3.6)2 (15.4)0.052
Obesity class II–III, n (%)4 (2.9)0 (0.0)0.535
Compliance BGT 70–180 mg/dL, n (%)* 115 (80.4)8 (57.1)0.044
Hypoglycemia <70 mg/dL, n (%)38 (26.6)12 (85.7)<0.001
Hyperglycemia >180 mg/dL, n (%)116 (81.1)14 (100.0)0.074
BGT – blood glucose target; BMI – body mass index; DM – diabetes mellitus; HTx – heart transplantation; MR – myocardial revascularization; SAH – systemic arterial hypertension; SD=standard deviation.
* Defined as maintaining glucose values within this range in ≥70% of measurements.
# BMI was missing in 5 cases.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750