24 May 2026 : Meta-Analysis
Utility of Acupuncture Therapy for Adult Chronic Daily Headache Prophylaxis: A Systematic Review and Meta-Analysis
Yuxi Nie ABCDEFG 1, Ruiyi Jing ABCDEFG 2, Ziyi Song DEF 1, Hong Zheng DEG 1*DOI: 10.12659/MSM.952359
Med Sci Monit 2026; 32:e952359
Table 5 GRADE evidence profile for all outcomes (follow-up period).
| No. of studies | Certainty assessment | |||||
|---|---|---|---|---|---|---|
| Study design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | |
| 3 | Randomized trials | Serious | Not serious | Not serious | Not serious | None |
| 8 | Randomized trials | Serious | Not serious | Not serious | Not serious | None |
| 8 | Randomized trials | Serious | Not serious | Not serious | Not serious | None |
| 5 | Randomized trials | Serious | Not serious | Not serious | Not serious | None |
| 6 | Randomized trials | Serious | Not serious | Not serious | Not serious | None |
| 3 | 102 | 100 | – | SMD 0.47 lower (0.94 lower to 0 higher) | ⊕⊕⊕○ Moderate | |
| 8 | 302 | 293 | – | SMD 0.7 lower (0.96 to 0.43 lower) | ⊕⊕⊕○ Moderate | |
| 8 | 285 | 279 | – | SMD 1.11 lower (1.93 to 0.29 lower) | ⊕⊕⊕○ Moderate | |
| 5 | 150 | 150 | – | SMD 1.83 lower (3.02 to 0.64 lower) | ⊕⊕⊕○ Moderate | |
| 6 | 155 | 155 | – | SMD 0.6 lower (1.05 to 0.16 lower) | ⊕⊕⊕○ Moderate | |