14 July 2026 : Clinical Research
Association Between Total Cholesterol–to–High-Density Lipoprotein Ratio and Gestational Hypertension: A Case-Control Study
Jin Yang BE 1, Zhiwei Ouyang F 2, Qiong Tang CD 3, Xiaofeng Kuang DF 1, Tian Ni BD 1, Xiang Shi AC 4*DOI: 10.12659/MSM.952395
Med Sci Monit 2026; 32:e952395
Table 1 Baseline characteristics of study participants by GH status.
| Variables | Total (n=614) | Normotensive pregnancy (n=307) | GH (n=307) | P values |
|---|---|---|---|---|
| Age, years | 32.0 (28.0, 35.0) | 32.0 (27.0, 34.5) | 32.0 (28.0, 36.0) | 0.118 |
| WBC, ×10/L | 8.50 (7.29, 9.92) | 8.24 (6.91, 9.61) | 8.88 (7.51, 10.21) | <0.001 |
| RBC, ×10/L | 4.26 (4.01, 4.54) | 4.18 (3.95, 4.46) | 4.35 (4.10, 4.64) | <0.001 |
| HGB, g/L | 126.00 (118.00, 133.00) | 123.00 (116.00, 131.00) | 127.00 (118.00, 135.00) | <0.001 |
| HCT,% | 36.65 (34.40, 38.77) | 35.90 (33.90, 37.80) | 37.50 (35.50, 39.50) | <0.001 |
| PLT, ×10/L | 252.00 (214.25, 293.75) | 242.00 (211.00, 290.50) | 260.00 (219.00, 294.50) | 0.039 |
| Neutrophils, ×10/L | 6.10 (5.12, 7.40) | 5.84 (4.77, 7.25) | 6.46 (5.36, 7.54) | <0.001 |
| Lymphocytes, ×10/L | 1.72 (1.41, 2.06) | 1.67 (1.38, 2.00) | 1.76 (1.46, 2.10) | 0.013 |
| Monocytes, ×10/L | 0.43 (0.35, 0.52) | 0.42 (0.34, 0.52) | 0.44 (0.37, 0.52) | 0.065 |
| RDW | 13.00 (12.60, 13.60) | 13.00 (12.25, 13.65) | 13.00 (12.60, 13.60) | 0.156 |
| TC, mmol/L | 4.61 (4.10, 5.23) | 4.55 (4.04, 5.19) | 4.65 (4.12, 5.28) | 0.135 |
| TG, mmol/L | 1.59 (1.22, 2.11) | 1.58 (1.25, 2.00) | 1.60 (1.17, 2.20) | 0.675 |
| HDL-C, mmol/L | 1.39 (1.20, 1.63) | 1.43 (1.21, 1.70) | 1.36 (1.19, 1.58) | 0.014 |
| LDL-C, mmol/L | 2.41 (2.00, 2.89) | 2.35 (1.98, 2.75) | 2.47 (2.07, 2.97) | 0.005 |
| TC/HDL-C | 3.36 (2.92, 3.79) | 3.22 (2.77, 3.71) | 3.42 (3.06, 3.88) | <0.001 |
| Data are presented as median (1 quartile, 3 quartile) for skewed variables. The Mann-Whitney U test was used to compare differences between groups. Abbreviations: GH, gestational hypertension; WBC, white blood cells; RBC, red blood cells; HGB, hemoglobin; HCT, hematocrit; PLT, platelets; RDW, red cell distribution width; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol. | ||||