14 July 2026 : Clinical Research
Association Between Total Cholesterol–to–High-Density Lipoprotein Ratio and Gestational Hypertension: A Case-Control Study
Jin Yang BE 1, Zhiwei Ouyang F 2, Qiong Tang CD 3, Xiaofeng Kuang DF 1, Tian Ni BD 1, Xiang Shi AC 4*DOI: 10.12659/MSM.952395
Med Sci Monit 2026; 32:e952395
Table 2 Association between TC/HDL-C ratio and GH: logistic regression models and trend tests.
| TC/HDL-C | GH OR (95% CI) | |||||
|---|---|---|---|---|---|---|
| Model 1 | P value | Model 2 | P value | Model 3 | P value | |
| Continuous | 1.46 (1.18~1.80) | <0.001 | 1.46 (1.18~1.80) | <0.001 | 1.44 (1.11~1.88) | 0.006 |
| Quantile | ||||||
| Q1 | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) | |||
| Q2 | 2.11 (1.25~3.57) | 0.005 | 2.07 (1.22~3.50) | 0.007 | 2.12 (1.21~3.74) | 0.009 |
| Q3 | 2.72 (1.62~4.57) | <0.001 | 2.62 (1.56~4.42) | <0.001 | 2.89 (1.62~5.15) | <0.001 |
| Q4 | 2.33 (1.38~3.92) | 0.001 | 2.32 (1.38~3.91) | 0.002 | 2.14 (1.18~3.58) | 0.012 |
| Q5 | 2.73 (1.62~4.60) | <0.001 | 2.71 (1.61~4.56) | <0.001 | 2.82 (1.48~5.37) | 0.002 |
| for trend | <0.001 | <0.001 | 0.006 | |||
| unadjusted. adjusted for age. adjusted for age, HCT, PLT, neutrophils, lymphocytes, monocytes, RDW, TG, and LDL-C. Abbreviations: GH, gestational hypertension; OR, odds ratio; CI, confidence interval; HCT, hematocrit; PLT, platelets; RDW, red cell distribution width; TG, triglycerides; LDL-C, low-density lipoprotein cholesterol. | ||||||