15 July 2026 : Clinical Research
Effect of Dexmedetomidine Hydrochloride Nasal Spray on Anxiety and Sleep in Patients Undergoing Gynecological Laparoscopic Surgery
Lin Zhao ABC 1, Xiaotian Zhang BDG 2, Xiaoxiao Li AB 3, Yipeng He AB 1, Zhouquan Wu AF 1, Liang Zhu ABCDEG 1*DOI: 10.12659/MSM.952465
Med Sci Monit 2026; 32:e952465
Table 1 Comparison of baseline characteristics and anesthesia start time between the 2 groups.
| Control group | DEX group | P | |
|---|---|---|---|
| Age, median (IQR), y | 47 (16) | 45 (14) | 0.642 |
| BMI | 24.3±2.3 (22–26.6) | 23.9±1.8 (22.1–25.7) | 0.419 |
| ASA I (n,%) | 7, 17.5% | 5, 12.5% | 0.53 |
| Hypertension (n,%) | 9, 22.5% | 7, 17.5% | 0.575 |
| Diabetes (n,%) | 5, 12.5% | 5, 12.5% | 0.632 |
| Which was started at | 0.59 | ||
| 08: 00–11: 59 AM | 21 | 21 | |
| 12: 00–6: 00 PM | 19 | 19 | |
| Abbreviations: BMI, body mass index; ASA, American Society of Anesthesiologists physical status classification; DEX, dexmedetomidine; IQR, interquartile range. Data are presented as mean±SD (min–max). | |||