15 July 2026 : Clinical Research
Effect of Dexmedetomidine Hydrochloride Nasal Spray on Anxiety and Sleep in Patients Undergoing Gynecological Laparoscopic Surgery
Lin Zhao ABC 1, Xiaotian Zhang BDG 2, Xiaoxiao Li AB 3, Yipeng He AB 1, Zhouquan Wu AF 1, Liang Zhu ABCDEG 1*DOI: 10.12659/MSM.952465
Med Sci Monit 2026; 32:e952465
Table 4 Objective sleep parameters on the night of surgery.
| Control group | DEX group | t | P | |
|---|---|---|---|---|
| Total sleep time, min | 474.46±97.77 (376.69–572.23) | 562.44±58.79 (503.65–621.23) | 2.41 | 0.03 |
| Proportion of deep sleep,% | 22.00±6.66 (15.34–28.66) | 28.56±7.18 (21.38–35.74) | 2.20 | 0.04 |
| Number of awakenings | 3.15±1.86 (1.29–5.01) | 1.33±1.22 (0.11–2.55) | −2.56 | 0.02 |
| Abbreviation: DEX, dexmedetomidine Data are presented as mean±SD (min–max). | ||||