Retrospective Study of Serum Vitamin D Levels and Metabolic-Associated Fatty Liver Disease in 222 Children and Adolescents Aged 6-18 Years With Obesity

27 April 2026 : Clinical Research

Ceren Yapar Gümüş

^{ABCDEFG 1*}, Yavuz Özer

^{ABE 2}, Yeliz Kaşko Arıcı

^{ACDE 3}

DOI: 10.12659/MSM.952489

Med Sci Monit 2026; 32:e952489

Authors information Article notes Copyright and License information

Introduction Material and Methods Results Discussion Conclusions References

Related articles Order reprints Share article Share by email

View HTML version

Table 4 Comparison of clinical and laboratory variables between non-MAFLD obesity and MAFLD obesity groups.

	Obesity without MAFLD			Obesity with MAFLD			P
	n	Mean	SD	n	Mean	SD	P
Age	87	12.97	3.13	135	13.62	2.85	0.109^a
25(OH)D, ng/mL	56	15.93	5.90	92	16.64	9.38	0.782^b
Weight SDS	87	3.02	0.90	133	3.45	1.11	^c
Height SDS	87	0.17	1.21	133	0.41	1.12	0.126^a
BMI SDS	87	2.86	0.54	133	3.06	0.63	^b
Serum glucose	86	91.63	7.78	132	98.36	35.72	0.087^a
Insulin	85	25.60	13.94	132	33.74	22.42	^b
Hba1c	77	5.39	0.23	126	5.66	1.01	^a
HOMA-IR	87	5.72	3.45	135	7.91	5.84	^b
ALT	85	20.43	10.77	131	36.06	32.99	^b
AST	85	20.00	5.61	130	29.89	22.12	^b
LDL-C	87	90.71	27.72	129	92.28	26.18	0.674^a
HDL-C	87	48.69	9.99	130	44.91	9.55	^a
Total cholesterol	87	162.14	28.84	129	161.98	31.46	0.970^a
Triglycerides	87	117.77	43.09	127	131.22	53.22	0.052^a
TSH	84	3.04	1.96	132	3.08	1.63	0.878^a
FT4	84	1.30	1.12	132	1.18	0.16	0.202^a
MAFLD – metabolic-associated fatty liver disease; SD – standard deviation; SDS – standard deviation score; BMI – body mass index; HOMA-IR – homeostasis model assessment of insulin resistance; HbA1c – glycated hemoglobin; ALT – alanine aminotransferase; AST – aspartate aminotransferase; HDL-C – high-density lipoprotein cholesterol; LDL-C – low-density lipoprotein cholesterol; TSH – thyroid-stimulating hormone; FT4 – free thyroxine; 25(OH)D – 25-hydroxyvitamin D. ^a test; ^b Mann-Whitney U test; ^c Welch test.

Back to the Article