Long-Term Durability and Dynamics of Anti-S-RBD IgG Response in Healthcare Workers: A Comparative Analysis of Homologous and Heterologous SARS-CoV-2 Vaccination Schedules in a 1-Year Serial Cross-Sectional Study

27 May 2026 : Clinical Research

Çiğdem Demirel

^{ABDEF 1}, Filiz Kibar

^{ABDEFG 1,2*}, Gülçin Dağlıoğlu

^{DE 2,3}, Salih Çetiner

^{DE 2}, Aslıhan Candevir

^{DE 4}, Ayşe Seza İnal

^{DE 5}, Sevinç Püren Yücel Karakaya

^{CD 6}, Özlem Görüroğlu Öztürk

^{DE 2,3}, Hatice Hale Gümüş

^{DE 1,2}, Tamer Cevat İnal

^{DE 2,3}

DOI: 10.12659/MSM.952930

Med Sci Monit 2026; 32:e952930

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Table 1 Participant groups according to vaccine combinations.

Group code	n	Vaccination schedule
SSS	39	Three homologous doses of CoronaVac (inactivated)
BBB	67	Three homologous doses of BNT162b2 (mRNA)
SSB	60	Two doses of CoronaVac followed by 1 booster dose of BNT162b2
SSBB	90	Two doses of CoronaVac followed by 2 booster doses of BNT162b2
SSBBB	51	Two doses of CoronaVac followed by 3 booster doses of BNT162b2

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