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Medical Science Monitor Basic Research


eISSN: 1643-3750

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Analysis of survival factors in patients with advanced-stage gastric adenocarcinoma.

S├╝leyman Alici, Serap Kaya, Mustafa Izmirli, Ilyas Tuncer, Ilyas Tuncer, Hanefi Ozbek, Hayriye Sayarlioglu

Med Sci Monit 2006; 12(5): CR221-229

ID: 450292

Background: Prognosis in patients with gastric cancer is determined bythe tumor itself, as well as certain patient-related factors. Material/Methods: In this study, 138 patientswith high-grade gastric adenocarcinoma who were admitted to our hospital between September 1999 and April2002 were retrospectively evaluated in terms of the effects of clinicopathological parameters and treatmentapproaches on survival by single and multiple variable analyses. Patients histopathologically diagnosedas having gastric adenocarcinomas with stage IV M[sub]0 (without distant organ metastasis) or stage IV M[sub]1[/sub](with distant organ metastasis) were included in the study. Results: Overall median survival time was3.1 months and three-year survival rate was 8%. With single variable analysis, body mass index (BMI),clinical stage, surgery, type of surgery, and serum level of albumin were significant prognostic factorsrelated to overall median survival time. Gender, clinical stage, surgery, type of surgery, hemoglobinconcentration, and serum level of albumin were found to be significant prognostic factors related tosurvival without progression (p

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