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15 June 2020: Clinical Research

LncRNA LINC00152 Increases the Aggressiveness of Human Retinoblastoma and Enhances Carboplatin and Adriamycin Resistance by Regulating MiR-613/Yes-Associated Protein 1 (YAP1) Axis

Ying Wang CDE* , Danli Xin ABCE , Lei Zhou BCDF

DOI: 10.12659/MSM.920886

Med Sci Monit 2020; 26:e920886

Figure 7 LINC00152 promoted YAP1 expression in retinoblastoma cells by targeting miR-613. (A–C) The protein and mRNA expression levels of YAP1 in Y79 and Weri-RB-1 cells transfected with si-NC, si-LINC00152#1, si-LINC00152#1+anti-miR-NC, or si-LINC00152#1+anti-miR-613 were detected by western blot and RT-qPCR assays, correspondingly. (D) Correlation analysis between LINC00152 and YAP1 was executed in retinoblastoma tissues. ** P<0.01. RT-qPCR – real-time quantitative polymerase chain reaction.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750