16 July 2020 : Animal Research
Alisma Shugan Decoction (ASD) Ameliorates Hepatotoxicity and Associated Liver Dysfunction by Inhibiting Oxidative Stress and p65/Nrf2/JunD Signaling Dysregulation In Vivo
Yunfeng Sun12AEG, Honghua Pan12CD, Shenghui Shen23ABCF, Zhongni Xia12BC, Zhongmin Yu2ABCD, ChengLe Li12F, Pingping Sun12DEG, Chuanwei Xin12DG*DOI: 10.12659/MSM.921738
Med Sci Monit 2020; 26:e921738
Figure 1 ASD ameliorated thioacetamide-induced hepatotoxicity and associated hepatic dysfunction in vivo. Graphical representations of the effect of 50 mg/kg ASD on (A) TAA-induced ALT or AST elevation, (B) rat liver weight, and (C) rat body weight. (D) Kaplan-Meier plot of the effect of 50 mg/kg ASD on the rat survival rate. TAA – thioacetamide; ASD – Alisma Shugan Decoction; ALT – alanine transaminase; AST – aspartate transaminase. * p<0.05; ** p<0.01; *** p<0.001.