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16 July 2020 : Animal Research  

Alisma Shugan Decoction (ASD) Ameliorates Hepatotoxicity and Associated Liver Dysfunction by Inhibiting Oxidative Stress and p65/Nrf2/JunD Signaling Dysregulation In Vivo

Yunfeng Sun12AEG, Honghua Pan12CD, Shenghui Shen23ABCF, Zhongni Xia12BC, Zhongmin Yu2ABCD, ChengLe Li12F, Pingping Sun12DEG, Chuanwei Xin12DG*

DOI: 10.12659/MSM.921738

Med Sci Monit 2020; 26:e921738

Figure 2 ASD reversed TAA-induced liver injury and fibrogenesis in liver injury model rats. (A) Images showing the effect of TAA alone or with ASD on the liver morphohistology in the liver injury model rats. Images of the effect of TAA alone or with ASD on the (B) picrosirius red-stained collagen fibers, and (C) α-SMA expression. Graphs showing how TAA alone or with ASD affected the (D) fibrosis score and (E) collagen area in the liver injury model rats. *** p<0.001.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750