16 July 2020: Animal Study
Alisma Shugan Decoction (ASD) Ameliorates Hepatotoxicity and Associated Liver Dysfunction by Inhibiting Oxidative Stress and p65/Nrf2/JunD Signaling Dysregulation
Yunfeng Sun 12AEG , Honghua Pan 12CD , Shenghui Shen 23ABCF , Zhongni Xia 12BC , Zhongmin Yu 2ABCD , ChengLe Li 12F , Pingping Sun 12DEG* , Chuanwei Xin 12DG*DOI: 10.12659/MSM.921738
Med Sci Monit 2020; 26:e921738
Figure 2 ASD reversed TAA-induced liver injury and fibrogenesis in liver injury model rats. (A) Images showing the effect of TAA alone or with ASD on the liver morphohistology in the liver injury model rats. Images of the effect of TAA alone or with ASD on the (B) picrosirius red-stained collagen fibers, and (C) α-SMA expression. Graphs showing how TAA alone or with ASD affected the (D) fibrosis score and (E) collagen area in the liver injury model rats. *** p<0.001.