01 August 2020 : Clinical Research
Streptococcus bovis Contributes to the Development of Colorectal Cancer via Recruiting CD11b⁺TLR-4⁺ Cells
Qun Deng1ABCDEFG*, Changjian Wang2BC, Kailin Yu3DE, Yahui Wang1EF, Qinyan Yang2CD, Jingjing Zhang1FG, Xiaoping Xu4AGDOI: 10.12659/MSM.921886
Med Sci Monit 2020; 26:e921886
Figure 3 Streptococcus bovis contribute to the development of CRC by recruiting TLR-4+CD11b+ cells. (A) Relative mRNA expression of IL-6, Scyb, Ptgs2, IL-1β, TNF, and Ccl2 (Model group n=12; S. bovis group, n=12). (B) The gating methods with density plots for intratumoral myeloid cells. (C) Percentage and count of colonic TLR-4+CD11b+ cells (Control group, n=8; Model group, n=12; S. bovis group, n=12). * P<0.05, ** P<0.01.