Figure 2 Associations of CUBN mRNA expression with clinicopathological features in CRC. (A) CUBN mRNA expression was significantly associated with T stage, and as T stage increased, the mRNA expression of CUBN tended to be higher. (B–D) Expression of CUBN mRNA in clinical stage IV or N2 or M1 was remarkably higher than that in stage I/II/III or N0/1 or M0. (F) Patients who accepted radiotherapy tended to express lower CUBN than those who did not. (E) There was no significant association between CUBN expression in MSI-H and MSS. * p<0.05, ** p<0.01, *** p<0.001.