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21 July 2020: Lab/In Vitro Research

Silencing of Long Non-Coding RNA (LncRNA) Non-Coding RNA Activated by DNA Damage (NORAD) Inhibits Proliferation, Invasion, Migration, and Promotes Apoptosis of Glioma Cells via Downregulating the Expression of AKR1B1

Lun Luo ABE* , Chuan Chen ACD , Haiyong He DFG , Meiqin Cai BCFG , Cong Ling BCE

DOI: 10.12659/MSM.922659

Med Sci Monit 2020; 26:e922659

Figure 4 (A–C) NORAD silencing promoted apoptosis of glioma cells. (A) Flow cytometry analysis was used to assess the apoptotic rate of U251 cells. (B) The expression of apoptosis-related proteins was examined using western blotting. All experiments were repeated 3 times independently (n=3). ** P<0.01, *** P<0.001 versus si-NC. NORAD – noncoding RNA activated by DNA damage; mRNA – si-NC, negative control for NORAD siRNA.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750