20 June 2020>: Database Analysis
Special AT-rich Sequence Binding-Protein 1 (SATB1) Correlates with Immune Infiltration in Breast, Head and Neck, and Prostate Cancer
Hua Ge 1ABCDEF* , Yan Yan 2BCDE , Maozhao Yan 1CEF , Lingfei Guo 1EF , Kun Mao 1CFDOI: 10.12659/MSM.923208
Med Sci Monit 2020; 26:e923208
Figure 9 SATB1 expression correlated with macrophage polarization in BRAC, HNSC, and PRAD. Markers include CD86 and CSF1R of monocytes; CCL2, CD68, and IL10 of TAMs; NOS2, IRF5, and PTGS2 of M1 macrophages; and CD163, VSIG4, and MS4A4A of M2 macrophages. (A) Scatterplots of correlations between SATB1 expression and gene markers of M1 macrophages, M2 macrophages, TAMs, and monocytes in BRAC (n=1093). (B) Scatterplots of correlations between SATB1 expression and gene markers of M1 macrophages, M2 macrophages, TAMs, and monocytes in HNSC (n=520). (C) Scatterplots of correlations between SATB1 expression and gene markers of M1 macrophages, M2 macrophages, TAMs, and monocytes in PRAD (n=497). BRCA – breast invasive carcinoma; HNSC – head and neck cancer; PRAD – prostate adenocarcinoma; TAMs – tumor associated macrophages.