01 September 2020: Animal Study
Chlorogenic Acid Alleviates Allergic Inflammatory Responses Through Regulating Th1/Th2 Balance in Ovalbumin-Induced Allergic Rhinitis Mice
Feilin Dong ABE , Jun Tan CDE , Yi Zheng DF*DOI: 10.12659/MSM.923358
Med Sci Monit 2020; 26:e923358
Figure 4 Chlorogenic acid (CGA) regulated the balance of Th1/Th2-associtaed cytokines in NALF and nasal tissues of the mice. Th1-related cytokine levels of IFN-γ and IL-12, and Th2-related cytokine levels IL-4, IL-5, and IL-13 were measured by enzyme-linked immunosorbent assays (ELISA) in NALF (A–E) and nasal mucosa (F–J). n=10 each group. # P<0.05, ### P<0.001 vs,. control, * P<0.05, ** P<0.01, *** P<0.001 vs. OVA.