04 August 2020>: Lab/In Vitro Research
Role and Mechanism of Maresin-1 in Acute Lung Injury Induced by Trauma-Hemorrhagic Shock
Huayi Ma 1ABCDEFG* , Song Mo 1ABCDEFG* , Qushen Yi 1BCD , Junhua Lai 1BF , Huan Liu 1BEFG* , Zhanying Shi 2BEFG*DOI: 10.12659/MSM.923518
Med Sci Monit 2020; 26:e923518
Figure 3 MaR1 increased NO concentrations and iNOS levels in THS-induced lung tissues. MaR1 or physiological saline were injected into THS-induced lung injury models. (A) The levels of NO were assessed. (B) qRT-PCR was used to measure the iNOS mRNA levels. (C) Western blot assay was adopted to assess the iNOS protein expression. ** P<0.01 versus Sham; #, ## P<0.01 versus THS+saline group. MaR1 – Maresin-1; NO – nitrogen oxide; iNOS – inducible nitric oxide synthase; THS – trauma hemorrhagic shock; qRT-PCR – quantitative real-time polymerase chain reaction; mRNA – messenger RNA.