27 July 2020: Database Analysis
Fibrinogen-Like Protein 2 (FGL2) is a Novel Biomarker for Clinical Prediction of Human Breast Cancer
Yanyan Feng 1AC* , Chunguang Guo 2BC* , Hesong Wang 1B , Lu Zhao 1CF , Wei Wang 1C , Ting Wang 1BC , Yuyin Feng 3C , Kai Yuan 1BCDF* , Guangrui Huang 3AEG*DOI: 10.12659/MSM.923531
Med Sci Monit 2020; 26:e923531
Figure 4 The correlation between FGL2 expression and immune status in the tumor microenvironment. (A) The FGL2 expression level was positively correlated with infiltrating levels of B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and DCs in BRCA. (B) The FGL2 expression level was positively correlated with infiltrating levels of antitumor immune cells, such as activated CD8+ T cells, effector memory CD8+ T cells, Th1 cells, NK cells, activated CD4+ T cells, effector memory CD4+ T cells, NKT cells, and central memory CD4+ T cells. (ES – enrichment score; FDR – false discovery rate).