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27 July 2020: Database Analysis

Fibrinogen-Like Protein 2 (FGL2) is a Novel Biomarker for Clinical Prediction of Human Breast Cancer

Yanyan Feng 1AC* , Chunguang Guo 2BC* , Hesong Wang 1B , Lu Zhao 1CF , Wei Wang 1C , Ting Wang 1BC , Yuyin Feng 3C , Kai Yuan 1BCDF* , Guangrui Huang 3AEG*

DOI: 10.12659/MSM.923531

Med Sci Monit 2020; 26:e923531

Figure 5 Modular analysis of the protein–protein interaction (PPI) network complex. In the STRING database, 21 proteins were filtered in the network complex. The PPI module consisted of 21 nodes and 108 edges. The average local clustering coefficient was 0.78. The PPI enrichment P-value was less than 1.0e-16. The top 5 predicted functional partners were MS4A6A (score: 0.801), FGB (score: 0.781), FGG (score: 0.776), FGA (score: 0.768), and FGL1 (score: 0.748). The blue and purple edges are considered known interactions. Green, red, and deep blue edges are predicted interactions. Orange, black, and light blue represent text mining, coexpression, and protein homology, respectively.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750