01 September 2020 : Laboratory Research
Atorvastatin Enhances Effects of Radiotherapy on Prostate Cancer Cells and Xenograft Tumor Mice Through Triggering Interaction Between Bcl-2 and MSH2
Zhenhua He1ABCDEFG*, Jingmin Yuan1BCDEF, Fuhui Shen2BCDF, Fangang Zeng2BCDF, Ping Qi3BCD, Zhiping Wang4BCF, Zhenxing Zhai4BFDOI: 10.12659/MSM.923560
Med Sci Monit 2020; 26:e923560
Figure 7 Effects of irradiation (IR) and/or atorvastatin (AS) administration on tumor size and tumor weight of xenograft tumor mice. (A) Representative images for the subcutaneous tumor xenografts. (B) Statistical analysis for the tumor size in PC-3, DU145 and Lncap cells transplanted xenograft tumor mice models. (C) Statistical analysis for tumor weight in PC-3, DU145, and Lncap cells transplanted xenograft tumor mice models. * P<0.05 versus PC3 or DU145 or Lncap group at the same time point. # P<0.05 versus PC3+IR or DU145+IR or Lncap+IR group at the same time point.