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01 September 2020: Lab/In Vitro Research

Atorvastatin Enhances Effects of Radiotherapy on Prostate Cancer Cells and Xenograft Tumor Mice Through Triggering Interaction Between Bcl-2 and MSH2

Zhenhua He 1ABCDEFG** , Jingmin Yuan 1BCDEF* , Fuhui Shen 2BCDF , Fangang Zeng 2BCDF , Ping Qi 3BCD , Zhiping Wang 4BCF* , Zhenxing Zhai 4BF

DOI: 10.12659/MSM.923560

Med Sci Monit 2020; 26:e923560

Figure 8 Observation for the interaction between Bcl-2 and MSH2 in tumor tissues of xenograft tumor mice using immuno-fluorescence assay. (A) Expression of Bcl-2 and MSH2 in tumor tissues of PC3-transplanted xenograft tumor mice. (B) Expression of Bcl-2 and MSH2 in tumor tissues of DU145-transplanted xenograft tumor mice. (C) Expression of Bcl-2 and MSH2 in tumor tissues of Lncap-transplanted xenograft tumor mice. * P<0.05 versus PC3 or DU145 or Lncap group. # P<0.05 versus PC3+IR or DU145+IR or Lncap+IR group. The scale bars were illustrated in images.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750