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02 July 2020: Clinical Research

Nuclear Factor κB/MicroRNA-155 Upregulates the Expression Pattern of Cytokines in Regulating the Relapse of Chronic Sinusitis with Nasal Polyps and the Underlying Mechanism of Glucocorticoid

Jianbin Du 1BCE , Haijun Lv 2BC , Xin Dou 3BC , Zhongsheng Cao 1ADEF*

DOI: 10.12659/MSM.923618

Med Sci Monit 2020; 26:e923618

Figure 6 Expression of TNF-α, IL-1, IL-4, and IL-5 in mice model of Eos CRSwNP. (A–D) qRT-PCR results displayed after application of PDTC, miR-155 antagomir, or DEX, the expression of TNF-α, IL-1, IL-4, and IL-5 were all significantly decreased in Eos CRSwNP group. * P<0.05; ** P<0.01. TNF – tumor necrosis factor; IL – interleukin; qRT-PCR – quantitative real-time polymerase chain reaction; PDTC – pyrrolidine dithiocarbonate; DEX – dexamethasone.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750