02 July 2020 : Clinical Research
Nuclear Factor κB/MicroRNA-155 Upregulates the Expression Pattern of Cytokines in Regulating the Relapse of Chronic Sinusitis with Nasal Polyps and the Underlying Mechanism of Glucocorticoid
Jianbin Du1BCE, Haijun Lv2BC, Xin Dou3BC, Zhongsheng Cao1ADEF*DOI: 10.12659/MSM.923618
Med Sci Monit 2020; 26:e923618
Figure 6 Expression of TNF-α, IL-1, IL-4, and IL-5 in mice model of Eos CRSwNP. (A–D) qRT-PCR results displayed after application of PDTC, miR-155 antagomir, or DEX, the expression of TNF-α, IL-1, IL-4, and IL-5 were all significantly decreased in Eos CRSwNP group. * P<0.05; ** P<0.01. TNF – tumor necrosis factor; IL – interleukin; qRT-PCR – quantitative real-time polymerase chain reaction; PDTC – pyrrolidine dithiocarbonate; DEX – dexamethasone.