07 July 2020 : Laboratory Research
Induction and Regulation of the Immunoproteasome Subunit β5i (PSMB8) in Laryngeal and Hypopharyngeal Carcinoma Cells
Nan-Xiang Chen1BCEF, Kun Liu1BC, Xuan Liu2A, Xin-Xin Zhang1AD, Dong-yi Han1ADF*DOI: 10.12659/MSM.923621
Med Sci Monit 2020; 26:e923621
Figure 1 Upon stimulation with cytokines (e.g., IFN-γ), the constitutively expressed β-subunits (β1, β2, and β5) of the 20S constructive proteasome are replaced by their inducible counterparts, β1i, β2i, and β5i, respectively, which form the 20S immunoproteasome (i20S).