Figure 2 Expression of MCM genes across different types of cancers (A) Transcription levels of MCMs in twenty human cancers compared with normal tissue were obtained from ONCOMINE, with the gene rank ≤ top 5%, fold change ≥2 and threshold of P≤0.001. Significant mRNA underexpression or overexpression of MCMs was shown as blue or red cell. Cancer types are organized by their tissue of origin, and the degree of color was determined by the gene rank percentile of the highest-ranking analyses. (B) MCMs expression levels in breast cancer compared with normal tissues in the GEPIA database.