17 October 2020 : Clinical Research
Brain-Derived Neurotrophic Factor Inhibits the Wound-Healing and Cell Proliferative Ability of Human Airway Epithelial Cells in Asthmatic Children
Shuguang Jing1AB, Xinghua Li1CE, Wei Liu2DE, Xia Li1F*DOI: 10.12659/MSM.923680
Med Sci Monit 2020; 26:e923680
Figure 1 The expression of BDNF in HAECs of asthmatic children was higher than that in the healthy control group. (A) qRT-PCR was used to detect the mRNA expressions of BDNF in newly separated asthmatic HAECs and healthy control HAECs. (B) The protein expression of BDNF in asthmatic and healthy controls was measured through western blot. &&& P<0.001 versus HC, *** P<0.001 versus HC1, ^^^ P<0.001 versus HC2, ### P<0.001 versus HC3, n=3. BDNF – brain-derived neurotrophic factor; qRT-PCR – quantitative real-time reverse transcription polymerase chain reaction; mRNA – messenger RNA; HAECs – human airway epithelial cells; HC – healthy controls.