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17 October 2020: Clinical Research

Brain-Derived Neurotrophic Factor Inhibits the Wound-Healing and Cell Proliferative Ability of Human Airway Epithelial Cells in Asthmatic Children

Shuguang Jing 1AB* , Xinghua Li 1CE* , Wei Liu 2DE , Xia Li 1F*

DOI: 10.12659/MSM.923680

Med Sci Monit 2020; 26:e923680

Figure 1 The expression of BDNF in HAECs of asthmatic children was higher than that in the healthy control group. (A) qRT-PCR was used to detect the mRNA expressions of BDNF in newly separated asthmatic HAECs and healthy control HAECs. (B) The protein expression of BDNF in asthmatic and healthy controls was measured through western blot. &&& P<0.001 versus HC, *** P<0.001 versus HC1, ^^^ P<0.001 versus HC2, ### P<0.001 versus HC3, n=3. BDNF – brain-derived neurotrophic factor; qRT-PCR – quantitative real-time reverse transcription polymerase chain reaction; mRNA – messenger RNA; HAECs – human airway epithelial cells; HC – healthy controls.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750