17 October 2020 : Clinical Research
Brain-Derived Neurotrophic Factor Inhibits the Wound-Healing and Cell Proliferative Ability of Human Airway Epithelial Cells in Asthmatic Children
Shuguang Jing1AB, Xinghua Li1CE, Wei Liu2DE, Xia Li1F*DOI: 10.12659/MSM.923680
Med Sci Monit 2020; 26:e923680
Figure 2 Wound closure and cell proliferation after wounding is impaired in asthmatic HAECs. (A) A mechanical injury model was established to assess wound closure. (B) Cell proliferation of asthmatic and normal HAECs was assayed through 3H-thymidine incorporation experiments. (C) The protein expression of CCND1 was measured via western blot. ^^ P<0.01, ^^^ P<0.001 versus HC, *** P<0.001 versus Control, n=3. HAECs – human airway epithelial cells; HC – healthy controls.