11 August 2020 : Review article
Current Status of Research on the Role of Circular RNAs in Hepatocellular Carcinoma and Clinical Implications
Ren-Chao Zou1E, Ling-Lin Li23CDE, Hong-Ling Yuan2A*DOI: 10.12659/MSM.923832
Med Sci Monit 2020; 26:e923832
Background
Overview of circRNA
Properties of circRNAs
Roles of circRNAs
Sponges of miRNA
CircRNAs-binding proteins
circRNAs Regulate Alternative Splicing, Transcription and Translation
Potential to Encode Proteins
circRNAs in Diseases
Overview of HCC
Roles of circRNAs in HCC
Tumor Inhibition
Tumor Promotion
Biomarker
Conclusions
References
Figure 2 The function of circRNAs in HCC carcinogenesis. This graph demonstrates the role of circRNAs in HCC carcinogenesis, including positive and negative effects, respectively.