07 July 2020 : Laboratory Research
Chlamydial-Secreted Protease Chlamydia High Temperature Requirement Protein A (cHtrA) Degrades Human Cathelicidin LL-37 and Suppresses Its Anti-Chlamydial Activity
Xiaohua Dong1AB, Wanxing Zhang2CE, Jianmei Hou3DF, Miaomiao Ma2DF, Congzhong Zhu4DF, Huiping Wang2AG, Shuping Hou2AG*DOI: 10.12659/MSM.923909
Med Sci Monit 2020; 26:e923909
Figure 5 cHtrA cleavage of LL-37 reverses anti-chlamydial activity on D and MoPn strains. C. trachomatis serovar D and MoPn strains were used to evaluate the cHtrA-mediated blockade of LL-37 anti-chlamydial activity. The colors of the tubes represent different experiment operates, and the details are contained in the legends. * P<0.05, ** P<0.01.