30 August 2020>: Lab/In Vitro Research
Honokiol Suppression of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastric Cancer Cell Biological Activity and Its Mechanism
Yidan Yan 1ABC , Jianmin Xu 2CDE , Guoxin Mao 3EFG*DOI: 10.12659/MSM.923962
Med Sci Monit 2020; 26:e923962
Figure 2 Honokiol (Hon) affected HER2-positive cell proliferation and apoptosis. Control: Untreated cells. Hon-L: Cells treated with low-dose Hon. Hon-M: Cells treated with middle-dose Hon. Hon-H: Cells treated with high-dose Hon. (A) The cell viability of different cell lines at different time points by cell-counting kit 8 (CCK-8) assay. ** P<0.01, *** P<0.001 compared with control group; # P<0.05 compared with Hon-L group; & P<0.05 compared with Hon-M group. (B) Cell apoptosis rate of different cell lines by flow cytometry. ** P<0.01, *** P<0.001 compared with control group; # P<0.05 compared with Hon-L group; & P<0.05 compared with Hon-M group.