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27 June 2020: Animal Study

Pyrroloquinoline Quinone Inhibits Oxidative Stress in Rats with Diabetic Nephropathy

Min Zhang 12ACD , Jiangzhao Zhang 3BE , Yan Xiong 2CF , Jiaqing Peng 2BF , Xiaoyan Wu 1AEG*

DOI: 10.12659/MSM.924372

Med Sci Monit 2020; 26:e924372

Figure 1 PQQ inhibits the structural and functional changes induced by STZ in DN. (A) Serum BUN. (B) Serum SCr. (C) Blood glucose. (D) Western blot detects collagen I expression. (E) H&E and T-col staining (magnification: 200×). * Compared with the control group, P<0.05; # Compared with the DN group, P<0.05. PQQ – pyrroloquinoline quinone; STZ – streptozocin; DN – diabetic nephropathy; BUN – blood urea nitrogen; SCr – serum creatinine; H&E – hematoxylin and eosin.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750