13 September 2020: Animal Study
AEB-071 Ameliorates Muscle Weakness by Altering Helper T Lymphocytes in an Experimental Autoimmune Myasthenia Gravis Rat Model
Feng Jing 1AE , Wei Huang 1BC , Qian Ma 1BC , Sheng-jie Xu 1BC , Chang-jin Wu 2BC , Yu-xiu Guan 2BC , Bing Chen 1A*DOI: 10.12659/MSM.924393
Med Sci Monit 2020; 26:e924393
Figure 1 Assessment of the EAMG rat model. (A) Lennon scores were increased in EAMG models compared to control animals. (B) Body weight was reduced in EAMG models compared to the control group. (C) Levels of serum anti-AChR were increased in EAMG models compared to control animals as determined by ELISA analysis at 10 weeks after establishment of the EAMG model. The results are expressed as mean±SD (n=5 rats/group). * p<0.05 compared to control group.