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02 August 2020: Database Analysis

Prognostic Implications of Novel Gene Signatures in Gastric Cancer Microenvironment

Mengyu Sun 1ACE , Jieping Qiu 1BCF , Huazheng Zhai 1BDF , Yaoqun Wang 1DF , Panpan Ma 1EF , Mengying Li 1E , Bo Chen 2AG*

DOI: 10.12659/MSM.924604

Med Sci Monit 2020; 26:e924604

Figure 2 Differentially expressed genes (DEGs) with immune/stromal score in stomach adenocarcinoma (STAD). (A) According to immune score, 1051 genes were high-expressed and 236 genes down-expressed in the high score group compared with the low score group (B) Similarly, 1591 high-expressed genes and 427 down-expressed genes were obtained based on stromal score. (C, D) In total, 769 DEGs were synchronously high-expressed in both the high score groups, while 150 genes were commonly down-expressed. (E) Heat map including 919 DEGs showed distinct gene expression profiles in STAD.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750