30 October 2020>: Clinical Research
Effect of Whole-Brain and Intensity-Modulated Radiotherapy on Serum Levels of miR-21 and Prognosis for Lung Cancer Metastatic to the Brain
Zhensheng Zhu 1AEG** , Qiurong Li 2ABD* , Mingjuan Xu 3CD , Zhongliang Qi 1BFDOI: 10.12659/MSM.924640
Med Sci Monit 2020; 26:e924640
Figure 1 Comparison of overall survival (OS) in patients with brain metastasis (BM) from lung cancer treated with whole-brain radiotherapy (WBRT) or intensity-modulated radiotherapy (IMRT). (A) Higher OS rates were seen in patients with BM from lung cancer treated with IMRT than in those treated with WBRT (hazard ratio [HR]=5.550, P=0.0185). (B) Higher OS rates also were seen in patients with BM from lung cancer that expressed low levels of miR-21 (HR=8.471, P=0.0372).