02 September 2020 : Database Analysis
A Novel Risk Model Based on Autophagy Pathway Related Genes for Survival Prediction in Lung Adenocarcinoma
Fan Zhang1ABCG, Suzhen Xie1DE, Zhenyu Zhang1C, Huanhuan Zhao1E, Zijun Zhao1F, Haiying Sun2G, Jiao Zheng1A*DOI: 10.12659/MSM.924710
Med Sci Monit 2020; 26:e924710
Figure 4 Prognostic index of 5 APRGs. (A) Lasso regression of 5 APRGs using the OS model. (B) Lasso co-efficient profiles of 5 APRGs by optimal lambda. Kaplan-Meier plot represents that patients in the high-risk group (red line) had significantly shorter overall survival time than those in the low-risk group (blue line). (C) Left: training group (D) Right: testing group. Time-dependent ROC curve analysis shows AUC values for OS in LUAD patients. (E) Left: training group. (F) Right: testing group. APRGs – autophagy-pathway-related genes; ROC – receiver-operator characteristic; AUC – area under the curve; OS – overall survival. LUAD – lung adenocarcinoma.