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24 August 2020 : Laboratory Research  

Olmutinib Reverses Doxorubicin Resistance in ETS1-Overexpressing Leukemia Cells

Jiansheng Zhong1ABE*, Jinli Zhang2AB, Xiaoyang Yu3BF, Xing Zhang1CD, Linping Dian1CD

DOI: 10.12659/MSM.924922

Med Sci Monit 2020; 26:e924922

Figure 3 The effect of olmutinib on apoptosis rate in K562 and K562/ADR cell lines overexpressing ETS1. Cell apoptosis of K562 (A) and K562/ADR (B) cells in different groups was assessed by flow cytometry (n=3). *** P<0.001 vs. Oe-NC+Dox; ## P<0.01 and ### P<0.001 vs. Oe-ETS1+Dox. Oe-NC – overexpression-negative control; Oe-ETS1 – overexpression-ETS1; Dox – doxorubicin; Olm – olmutinib.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750