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04 August 2020: Database Analysis

TPX2 Promotes Metastasis and Serves as a Marker of Poor Prognosis in Non-Small Cell Lung Cancer

Fang Zhou 1ACE , Meng Wang 1D , Mijiti Aibaidula 2F , Zhiguo Zhang 2D , Abudusaimaiti Aihemaiti 2B , Rezhake Aili 2B , Hao Chen 2B , Shuangfeng Dong 2B , Wei Wei 2B , Abulizi Maimaitiaili 2ACG*

DOI: 10.12659/MSM.925147

Med Sci Monit 2020; 26:e925147

Figure 2 Correlation of TPX2 with NSCLC tumor characteristics in clinical samples. (A) TPX2 staining was weakly positive and strongly positive in nonmetastatic and metastatic lung cancer tissues, separately. (B) TPX2 expression was significantly upregulated in the metastatic NSCLC samples compared with the nonmetastatic NSCLC samples. (C) TPX2 expression was significantly increased with the NSCLC tumor size. (D) TPX2 expression was significantly increased with the NSCLC clinical stage. (E) Overall survival analysis of TPX2 on patients with NSCLC (mean±SD; ** P<0.01).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750